Acetic Acid

Acetic Acid

SCHEMBL29779174

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nearest known ligand 0.36

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123576 0.89 LMNA (0.41) LMNA
SCHEMBL30927822 0.87 ALDH1A1 (0.30) ALDH1A1TDP1
Acrylic Acid SCHEMBL27994511 0.85 LMNA (0.36) ALDH1A1LMNA
Acrylic Acid SCHEMBL31059850 0.85 LMNA (0.36) ALDH1A1LMNA
Acrylic Acid SCHEMBL29282689 0.85 LMNA (0.36) ALDH1A1LMNA
Acrylic Acid SCHEMBL31059854 0.85 LMNA (0.36) ALDH1A1LMNA
Methoxymethane SCHEMBL28147061 0.85 LMNA (0.38) LMNA
Mercaptopropionic Acid SCHEMBL29480053 0.82 ACE (0.34)
Propene SCHEMBL28161085 0.79 LMNA (0.33) LMNA
Methacrylic Acid SCHEMBL28971892 0.74 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022151922-A1 METHOD FOR IMPROVING CONSISTENCY OF ENERGY STORAGE DEVICE 深圳信达新能源科技有限公司 2022-07-21 WO disclosed