Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24825932 | 1.00 | MEN1 (0.45) | MEN1HTTKMT2ABCAT1BCAT2 | |
| SCHEMBL29779327 | 0.82 | MEN1 (0.47) | MEN1HTTKMT2ABCAT1BCAT2 | |
| SCHEMBL24826943 | 0.82 | MEN1 (0.47) | MEN1HTTKMT2ABCAT1BCAT2 | |
| SCHEMBL24824846 | 0.79 | BCAT1 (0.48) | BCAT1BCAT2ARALDH1A1 | |
| SCHEMBL24823987 | 0.79 | AR (0.46) | BCAT1BCAT2ARALDH1A1 | |
| SCHEMBL24825590 | 0.79 | BCAT1 (0.46) | BCAT1BCAT2AR | |
| SCHEMBL24823990 | 0.79 | AR (0.52) | MEN1KMT2ABCAT1BCAT2AR | |
| SCHEMBL24824852 | 0.74 | BCAT1 (0.49) | BCAT1BCAT2ARTBXA2RHPGD | |
| SCHEMBL29779335 | 0.74 | BCAT1 (0.49) | BCAT1BCAT2ARTBXA2RHPGD | |
| SCHEMBL24825907 | 0.73 | AR (0.48) | MEN1KMT2ABCAT1BCAT2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411381-A1 | PYRIMIDINEDIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | US | disclosed |
| EP-4038054-A1 | PYRIMIDINEDIONE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2022-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411381-A1 | PYRIMIDINEDIONE DERIVATIVES | DPYD, TYMP, TYMS | MEN1 1160/4885HTT 3306/4885KMT2A 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.