SCHEMBL29779335

SCHEMBL29779335

CCCOc1cc(C#N)c(Oc2ccccc2C)cc1NC(=O)OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 7/20 0.49
BCAT2 O15382 2/20 0.49
AR P10275 3/20 0.42
HPGD P15428 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
NLRP3 Q96P20 1/20 0.42
ALDH1A1 P00352 2/20 0.39
GAA P10253 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TBXA2R P21731 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
ALOX12 P18054 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24824852 1.00 BCAT1 (0.49) BCAT1BCAT2ARHPGDCYP1A2
SCHEMBL24823990 0.81 AR (0.52) BCAT1BCAT2ARHPGDALDH1A1
SCHEMBL24823987 0.81 AR (0.46) BCAT1BCAT2ARALDH1A1IMPDH2
SCHEMBL24825590 0.81 BCAT1 (0.46) BCAT1BCAT2ARSLC22A12
SCHEMBL24824846 0.81 BCAT1 (0.48) BCAT1BCAT2ARALDH1A1IMPDH2
SCHEMBL24825943 0.78 BCAT1 (0.55) BCAT1BCAT2ARIMPDH2
SCHEMBL24823981 0.78 BCAT1 (0.53) BCAT1BCAT2ARCYP1A2CYP2C9
SCHEMBL24825509 0.77 NLRP3 (0.48) BCAT1BCAT2ARHPGDCYP1A2
SCHEMBL29779328 0.77 NLRP3 (0.48) BCAT1BCAT2ARHPGDCYP1A2
SCHEMBL24825932 0.74 MEN1 (0.45) BCAT1BCAT2ARHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4038054-A1 PYRIMIDINEDIONE DERIVATIVES Bayer Aktiengesellschaft (DE) 2022-08-10 EP disclosed