Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | APAF1 | O14727 | 3/20 | 0.34 |
| ▸ | UBE2N | P61088 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22761834 | 0.77 | CYP3A4 (0.62) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| SCHEMBL19610233 | 0.76 | CYP1A1 (0.61) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| Bromide SCHEMBL22749446 | 0.76 | CYP1A1 (0.63) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| Bromide SCHEMBL30145064 | 0.75 | CYP1A1 (0.62) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| SCHEMBL22761851 | 0.69 | CYP1A1 (0.72) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| Bromide SCHEMBL22749642 | 0.68 | CYP1A1 (0.73) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| Bromide SCHEMBL22749641 | 0.68 | CYP1A1 (0.69) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| SCHEMBL22761685 | 0.67 | HTT (0.48) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| Bromide SCHEMBL4940305 | 0.66 | CYP1A1 (0.48) | MEN1KMT2ACYP1A1CYP1B1TP53 | |
| Bromide SCHEMBL4942000 | 0.66 | SMN1; SMN2 (0.55) | MEN1KMT2ACYP1A1CYP1B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251054-A1 | Analogues and Methods of Treating Rett Syndrome | UNIV CALIFORNIA (US) | 2022-08-11 | — | — | US | claimed |
| US-20220251054-A1 | Analogues and Methods of Treating Rett Syndrome | UNIV CALIFORNIA (US) | 2022-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251054-A1 | Analogues and Methods of Treating Rett Syndrome | MECP2, PAX3, PAX2 | MEN1 752/4885KMT2A 87/4885CYP1A1 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.