PAX2

Paired box protein Pax-2 · Q02962 · PAX2 on Sugi Atlas →

68 patent compounds predicted against PAX2, 24 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL24129236 SCHEMBL24129236 0.63 1/20
SCHEMBL24129343 SCHEMBL24129343 0.63 1/20
SCHEMBL24129395 SCHEMBL24129395 0.61 1/20
SCHEMBL18131066 SCHEMBL18131066 0.60 1/20
SCHEMBL24129415 SCHEMBL24129415 0.56 1/20
SCHEMBL24129329 SCHEMBL24129329 0.55 1/20
SCHEMBL24129211 SCHEMBL24129211 0.54 1/20
SCHEMBL24129327 SCHEMBL24129327 0.54 1/20
SCHEMBL24129393 SCHEMBL24129393 0.54 1/20
SCHEMBL14271007 SCHEMBL14271007 0.51 1/20
SCHEMBL24129332 SCHEMBL24129332 0.50 1/20
SCHEMBL3123741 SCHEMBL3123741 0.47 1/20
SCHEMBL353089 SCHEMBL353089 0.46 1/20
SCHEMBL7829394 SCHEMBL7829394 0.44 1/20
SCHEMBL5199168 SCHEMBL5199168 0.43 1/20
SCHEMBL7819692 SCHEMBL7819692 0.43 1/20
SCHEMBL10407276 SCHEMBL10407276 0.43 1/20
SCHEMBL10407277 SCHEMBL10407277 0.43 1/20
SCHEMBL22968432 SCHEMBL22968432 0.43 1/20
SCHEMBL24129416 SCHEMBL24129416 0.43 1/20

Clinical trials — most relevant to PAX2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study) PHASE3RECRUITING
Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma PHASE3RECRUITING
FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma PHASE1/PHASE2RECRUITING
Azacitidine After Allo Blood And Marrow Transplantation (BMT) for Chronic Myelogenous Leukemia (CML) PHASE2COMPLETED
Evolutionary Therapy for Rhabdomyosarcoma PHASE2ACTIVE_NOT_RECRUITING
Open-label Trial of SUBA™-Itraconazole (SUBA-Cap) in Subjects With Basal Cell Carcinoma Nevus Syndrome (BCCNS) PHASE2COMPLETED
Everolimus (RAD001) as Therapy for Patients With Systemic Mastocytosis PHASE2COMPLETED
Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer PHASE1/PHASE2SUSPENDED
Biomarkers in Patients With Advanced Rhabdomyosarcoma nanCOMPLETED
Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis. nanCOMPLETED
HIF-1α Stabilization As a Novel Therapeutical Approach for Sarcopenia. nanRECRUITING
Precision Medicine in Alzheimer's Disease : Integration of Resilience Metrics and Risk Factors - Validation Cohort BioCogBank-AD nanRECRUITING
Studying Protein Expression in Tissue Samples From Younger Patients With Rhabdomyosarcoma nanCOMPLETED
Role of HIF-1α in Skeletal Muscle Aging nanUNKNOWN
The Role of TBX3 in Human ES Cell Differentiation nanWITHDRAWN
RORC Genetic Polymorphism of Rheumatoid Arthritis nanCOMPLETED
B3 for NMD: Bench to Bedside and Back nanENROLLING_BY_INVITATION
X-chromosome Inactivation, Epigenetics and the Transcriptome nanCOMPLETED
Does Notch Regulate Glioma Proliferation ? nanCOMPLETED
Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes nanACTIVE_NOT_RECRUITING
Pathophysiology of Diabetic Gastroparesis nanUNKNOWN
The Role of CSF in Chiari II Brain Malformation nanNOT_YET_RECRUITING
Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid Tumor nanWITHDRAWN
Stem Cells in NF1 Patients With Tumors of the Central Nervous System nanWITHDRAWN
Study of Neurodegenerative Diseases Induced Stem Cells in Patients and Healthy Family Controls. nanUNKNOWN
Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With Rhabdomyosarcoma nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Gene Expression Profiles in Patients With Metastatic Pancreatic Cancer nanCOMPLETED
Evaluation of the Regeneration Capacity of Satellite Cells From the Quadriceps Compared to That of the Diaphragm nanCOMPLETED
Podocyts Integrity in Glomerular Diseases nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PAX2 binder may also engage these)

ProteinNameSimilarity
P32114 1.000 P32114 →
Q90268 1.000 Q90268 →
P47240 1.000 P47240 →
Q02548 1.000 Q02548 →
PAX8 Paired box protein Pax-8 1.000 landscape →
P24610 1.000 P24610 →
Q02650 1.000 Q02650 →
A0JMA6 1.000 A0JMA6 →
P47239 1.000 P47239 →
Q9YH95 1.000 Q9YH95 →
O57682 1.000 O57682 →
PAX3 Paired box protein Pax-3 (HuP2) 1.000 landscape →
O57685 1.000 O57685 →
Q2VL58 1.000 Q2VL58 →
P55771 1.000 P55771 →
Q00288 1.000 Q00288 →
Q2VL59 1.000 Q2VL59 →
Q2VL51 1.000 Q2VL51 →
Q2VL57 1.000 Q2VL57 →
P47238 0.999 P47238 →
Q6YHU8 0.999 Q6YHU8 →
Q2VL62 0.999 Q2VL62 →
P47242 0.999 P47242 →
Q645N4 0.999 Q645N4 →
P23759 0.998 P23759 →
Q2VL56 0.998 Q2VL56 →
Q2L4T2 0.998 Q2L4T2 →
P14653 0.998 P14653 →
O95677 0.998 O95677 →
Q2VL50 0.998 Q2VL50 →