Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689562 | 1.00 | MAPK1 (0.46) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL1505593 | 0.82 | MAPK1 (0.53) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL29220843 | 0.82 | KDM4E (0.50) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL31444518 | 0.82 | MAPK1 (0.49) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL4538933 | 0.82 | MAPK1 (0.49) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL24215426 | 0.81 | MAPK1 (0.47) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL114553 | 0.81 | ATM (0.51) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL30574354 | 0.81 | ATM (0.51) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL29104725 | 0.81 | KDM4E (0.53) | MAPK1ATMKDM4EL3MBTL1POLB | |
| SCHEMBL487571 | 0.81 | ATM (0.51) | MAPK1ATMKDM4EL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037670-A1 | 5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF | Tenaya Therapeutics, Inc. (US) | 2022-08-10 | — | — | EP | disclosed |