Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.69 |
| ▸ | BCHE | P06276 | 6/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.62 |
| ▸ | ACHE | P22303 | 4/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593092 | 1.00 | MPO (0.69) | MPOBCHECHRM2GRIN1GRIN2A | |
| SCHEMBL4859974 | 0.90 | BCHE (0.77) | MPOBCHECHRM2GRIN1GRIN2A | |
| SCHEMBL9081522 | 0.89 | BCHE (0.64) | MPOBCHECHRM2GRIN1GRIN2A | |
| SCHEMBL27593083 | 0.82 | MPO (0.66) | MPOBCHECHRM2GRIN1GRIN2A | |
| SCHEMBL8883322 | 0.82 | KDM4E (0.70) | BCHECHRM2GRIN1GRIN2AACHE | |
| SCHEMBL29463722 | 0.80 | SIGMAR1 (0.65) | — | |
| SCHEMBL5268648 | 0.80 | SIGMAR1 (0.65) | BCHE | |
| SCHEMBL9571819 | 0.80 | SIGMAR1 (0.65) | — | |
| SCHEMBL9079771 | 0.80 | BCHE (0.74) | MPOBCHE | |
| SCHEMBL8084265 | 0.79 | HTR2A (0.66) | BCHECHRM2GRIN1GRIN2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037668-A1 | SMALL MOLECULE INHIBITORS OF ID PROTEINS | Memorial Sloan Kettering Cancer Center (US) | 2022-08-10 | — | — | EP | disclosed |