Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10200847 | 0.76 | CCR1 (0.45) | CCR1CCR5CCR8L3MBTL1CYP1A2 | |
| SCHEMBL19698918 | 0.75 | ALDH1A1 (0.42) | KDM4EL3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL29779683 | 0.73 | KDM4E (0.43) | KDM4EL3MBTL1ALDH1A1MAPTCYP3A4 | |
| SCHEMBL19554482 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1MAPTTSHRRAB9A | |
| SCHEMBL7199668 | 0.70 | KDM4E (0.47) | CCR1CCR5CCR8KDM4EASPH | |
| SCHEMBL9684174 | 0.68 | KDM4E (0.50) | CCR1CCR5CCR8KDM4EASPH | |
| SCHEMBL30049082 | 0.68 | KDM4E (0.50) | CCR1CCR5CCR8KDM4EASPH | |
| SCHEMBL1541111 | 0.68 | KDM4E (0.46) | CCR1CCR5CCR8KDM4EASPH | |
| SCHEMBL14284234 | 0.68 | KDM4E (0.46) | KDM4EASPHKDM8MYCL3MBTL1 | |
| SCHEMBL23500420 | 0.67 | MYC (0.46) | KDM4EASPHKDM8MYCL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311902-B | Substituted imidazo [1,2-b ] pyridazines, imidazo [1,5-b ] pyridazines, related compounds, and uses thereof | BIAL研发投资股份有限公司 | 2022-07-15 | — | — | CN | disclosed |