Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGAV | P06756 | 2/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.52 |
| ▸ | GHSR | Q92847 | 2/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | TCF4 | P15884 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pseudostellarin H SCHEMBL31295693 | 0.93 | KEAP1 (0.55) | KEAP1ITGB3ITGAVITGB5ITGB1 | |
| Segetalin D SCHEMBL151348 | 0.85 | HDAC4 (0.54) | KEAP1HDAC4GHSRHDAC1 | |
| SCHEMBL30576709 | 0.84 | HDAC4 (0.58) | ITGB3ITGAVITGA5HDAC4HDAC1 | |
| SCHEMBL29412929 | 0.84 | HDAC4 (0.54) | HDAC4GHSR | |
| SCHEMBL29779778 | 0.83 | GHSR (0.52) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL28240936 | 0.83 | GHSR (0.52) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| Stylopeptide SCHEMBL31094295 | 0.83 | HDAC4 (0.53) | HDAC4HDAC1 | |
| SCHEMBL1519049 | 0.83 | ITGAV (0.47) | KEAP1ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL29884582 | 0.82 | HDAC4 (0.60) | HDAC4GHSRHDAC1 | |
| SCHEMBL24739370 | 0.82 | KEAP1 (0.46) | KEAP1ITGB3ITGAVITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114720568-A | Method for establishing fingerprint spectrum of radix pseudostellariae medicinal material and application thereof | 云南雷允上理想药业有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114720568-A | Method for establishing fingerprint spectrum of radix pseudostellariae medicinal material and application thereof | 云南雷允上理想药业有限公司 | 2022-07-08 | — | — | CN | disclosed |