Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.61 |
| ▸ | METAP1 | P53582 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | KDR | P35968 | 3/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273984 | 1.00 | METAP2 (0.61) | METAP2METAP1MEN1KMT2AKDR | |
| Hydrochloric Acid SCHEMBL7173513 | 0.96 | MEN1 (0.60) | METAP2METAP1MEN1KMT2AKDR | |
| Hydrochloric Acid SCHEMBL7173200 | 0.96 | MEN1 (0.60) | METAP2METAP1MEN1KMT2AKDR | |
| Hydrochloric Acid SCHEMBL7183099 | 0.96 | MEN1 (0.60) | METAP2METAP1MEN1KMT2AKDR | |
| Hydrochloric Acid SCHEMBL7178625 | 0.96 | MEN1 (0.60) | METAP2METAP1MEN1KMT2AKDR | |
| Hydrochloric Acid SCHEMBL7176548 | 0.96 | MEN1 (0.60) | METAP2METAP1MEN1KMT2AKDR | |
| Hydrochloric Acid SCHEMBL7174476 | 0.96 | MEN1 (0.60) | METAP2METAP1MEN1KMT2AKDR | |
| Hydrochloric Acid SCHEMBL7175864 | 0.96 | MEN1 (0.60) | METAP2METAP1MEN1KMT2AKDR | |
| SCHEMBL4814275 | 0.89 | CYP19A1 (0.56) | METAP2METAP1MEN1KMT2AKDR | |
| SCHEMBL1533891 | 0.88 | METAP2 (0.57) | METAP2METAP1MEN1KMT2AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153907-A1 | DOUBLE DYNAMIC POLYMERS | UNIVERSITÉ DE STRASBOURG (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153907-A1 | DOUBLE DYNAMIC POLYMERS | PCNA, DCLRE1A, MRE11 | METAP2 3805/4885METAP1 4382/4885MEN1 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.