Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 14/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20773015 | 1.00 | TRPM8 (0.79) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29779970 | 0.95 | TRPM8 (0.80) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20772754 | 0.95 | TRPM8 (0.80) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10270781 | 0.88 | TRPM8 (1.00) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13471448 | 0.86 | TRPM8 (1.00) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20772997 | 0.83 | TRPM8 (0.78) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29779965 | 0.83 | TRPM8 (0.78) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20773111 | 0.83 | TRPM8 (0.74) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29779972 | 0.83 | TRPM8 (0.74) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31490415 | 0.82 | TRPM8 (0.77) | TRPM8HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | BASF SE (DE) | 2022-09-06 | — | — | US | claimed |
| EP-4554572-A2 | MIXTURES AND USES OF (2E)-3-(1,3-BENZODIOXOL-5-YL)-N-PHENYL-N-(TETRAHYDRO-3-FURANYL)-2-PROPENAMIDE | Symrise AG (DE) | 2025-05-21 | — | — | EP | disclosed |
| EP-3675809-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022207944-A9 | NOVEL MIXTURES AND USES OF (2E)-3-(1,3-BENZODIOXOL-5-YL)-N-PHENYL-N-(TETRAHYDRO-3-FURANYL)-2-PROPENAMIDE | SYMRISE AG (DE) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022207944-A2 | NOVEL MIXTURES AND USES OF (2E)-3-(1,3-BENZODIOXOL-5-YL)-N-PHENYL-N-(TETRAHYDRO-3-FURANYL)-2-PROPENAMIDE | SYMRISE AG (DE) | 2022-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434220-B2 | Use of physiological cooling active ingredients, and compositions comprising such active ingredients | TRPM8, TRPM7, TRPM5 | TRPM8 1/4885HPGD 1710/4885NPC1 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.