Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.50 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23461171 | 1.00 | MKNK1 (0.62) | MKNK1MAPK1HTTLCKCCNT1 | |
| SCHEMBL29780227 | 0.72 | METAP2 (0.38) | — | |
| SCHEMBL23478145 | 0.72 | METAP2 (0.38) | — | |
| SCHEMBL23462206 | 0.71 | IDO1 (0.44) | — | |
| SCHEMBL29780223 | 0.71 | IDO1 (0.44) | — | |
| SCHEMBL1406620 | 0.69 | MAPK1 (1.00) | MKNK1MAPK1HTTLCKCCNT1 | |
| SCHEMBL1984025 | 0.69 | GRM5 (0.44) | — | |
| SCHEMBL23461094 | 0.68 | IDH1 (0.37) | — | |
| SCHEMBL29780205 | 0.68 | IDH1 (0.37) | — | |
| SCHEMBL16363256 | 0.67 | MKNK1 (0.73) | MKNK1MAPK1HTTLCKCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114760994-A | Inhibitors of HIF-2 alpha | 艾库斯生物科学有限公司 | 2022-07-15 | — | — | CN | disclosed |