Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 7/20 | 0.59 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.59 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.50 |
| ▸ | GRB2 | P62993 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463285 | 0.97 | NTSR2 (0.62) | NTSR1NTSR2LNPEPERAP2F2 | |
| SCHEMBL9294767 | 0.94 | NTSR2 (0.59) | NTSR1NTSR2LNPEPERAP2F2 | |
| SCHEMBL9294748 | 0.94 | NTSR2 (0.59) | NTSR1NTSR2LNPEPERAP2F2 | |
| SCHEMBL30578955 | 0.91 | LNPEP (0.58) | NTSR1NTSR2LNPEPERAP2NPY1R | |
| SCHEMBL29612288 | 0.91 | NTSR1 (0.60) | NTSR1NTSR2LNPEPERAP2F2 | |
| SCHEMBL29611893 | 0.90 | NTSR1 (0.61) | NTSR1NTSR2F2ACEMME | |
| SCHEMBL29386049 | 0.88 | LNPEP (0.66) | LNPEPERAP2ACEMMENPY1R | |
| SCHEMBL338636 | 0.88 | LNPEP (0.66) | LNPEPERAP2ACEMMENPY1R | |
| SCHEMBL29370934 | 0.88 | LNPEP (0.66) | LNPEPERAP2ACEMMENPY1R | |
| SCHEMBL29371447 | 0.88 | LNPEP (0.66) | LNPEPERAP2ACEMMENPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249605-A1 | Treatment of Mood and Anxiety Disorders | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2022-08-11 | — | — | US | disclosed |