Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ABL2 | P42684 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22609023 | 1.00 | AHR (0.52) | AHRFEN1SMN1; SMN2ABL1EGFR | |
| Potassium SCHEMBL3627554 | 0.96 | AHR (0.48) | AHRFEN1SMN1; SMN2ABL1EGFR | |
| SCHEMBL1921411 | 0.78 | AHR (0.50) | AHRSMN1; SMN2MAPTHTR2AHTR2C | |
| SCHEMBL30439700 | 0.77 | FEN1 (0.52) | AHRFEN1CYP2A6CCNB2CCNE2 | |
| SCHEMBL6008314 | 0.77 | FEN1 (0.52) | AHRFEN1CYP2A6CCNB2CCNE2 | |
| SCHEMBL2057104 | 0.77 | SMN1; SMN2 (0.43) | AHRSMN1; SMN2ABL1EGFRABL2 | |
| SCHEMBL7490077 | 0.76 | CYP2A6 (0.47) | AHRFEN1CYP2A6CCNB2CCNE2 | |
| SCHEMBL3853007 | 0.76 | TUBB4A (0.49) | AHRFEN1SMN1; SMN2EGFRCCNB2 | |
| SCHEMBL6008267 | 0.75 | ALDH1A1 (0.44) | AHRFEN1CYP2A6CCNB2CCNE2 | |
| SCHEMBL21884850 | 0.75 | AHR (0.47) | AHRSMN1; SMN2ABL1EGFRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2022-07-05 | — | — | CN | disclosed |