Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17699828 | 1.00 | ATM (0.43) | ATMMMP2WDR5FLT1FLT4 | |
| SCHEMBL55285 | 0.86 | CA1 (0.44) | HSD11B1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3600024 | 0.85 | ATM (0.49) | ATMMMP2WDR5FLT1FLT4 | |
| SCHEMBL17364184 | 0.85 | ATM (0.45) | ATMMMP2WDR5HSD11B1PGR | |
| SCHEMBL1369921 | 0.81 | CA2 (0.47) | ATMMMP2WDR5FLT1FLT4 | |
| SCHEMBL28605173 | 0.81 | ATM (0.43) | ATMMMP2WDR5HSD11B1PGR | |
| SCHEMBL263686 | 0.81 | ATM (0.46) | ATMMMP2KAT6AHSD17B2L3MBTL1 | |
| SCHEMBL4251866 | 0.80 | PLCG1 (0.56) | ATMMMP2WDR5PGREGFR | |
| SCHEMBL2555899 | 0.80 | ATM (0.42) | ATMMMP2WDR5HSD11B1PGR | |
| SCHEMBL1369364 | 0.79 | CA2 (0.50) | ATMMMP2WDR5HSD11B1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511209-B | Indole carboxamide compounds useful as kinase inhibitors | 百时美施贵宝公司 | 2022-07-05 | — | — | CN | disclosed |