Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398597 | 1.00 | KDM4E (0.66) | KDM4EGAAPOLBHSD17B10TDP1 | |
| SCHEMBL8806160 | 0.98 | GAA (0.69) | KDM4EGAAPOLBHSD17B10TDP1 | |
| SCHEMBL15122952 | 0.86 | GAA (0.62) | KDM4EGAAPOLBHSD17B10TDP1 | |
| SCHEMBL1479263 | 0.86 | KDM4E (0.51) | KDM4EGAAPOLBHSD17B10TDP1 | |
| SCHEMBL2332030 | 0.86 | KDM4E (0.51) | KDM4EGAAPOLBHSD17B10TDP1 | |
| SCHEMBL2307303 | 0.85 | ADRB1 (0.50) | KDM4EGAAPOLBHSD17B10TDP1 | |
| SCHEMBL30689191 | 0.85 | SMN1; SMN2 (0.59) | KDM4EGAAPOLBL3MBTL1TSHR | |
| SCHEMBL1665694 | 0.85 | SMN1; SMN2 (0.59) | KDM4EGAAPOLBL3MBTL1TSHR | |
| SCHEMBL1666026 | 0.83 | KDM4E (0.54) | KDM4EGAAPOLBHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL10318583 | 0.83 | ADRB1 (0.49) | KDM4EGAAPOLBHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136187-A | Novel anti-hepatitis B compound | 上海齐鲁制药研究中心有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-110475775-B | 4-pyridone compound or salt thereof, pharmaceutical composition containing 4-pyridone compound, and agent | 富士胶片株式会社 | 2023-05-09 | — | — | CN | disclosed |
| US-11390610-B2 | Piperazine derivatives as MAGL inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2022-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11390610-B2 | Piperazine derivatives as MAGL inhibitors | MAGI3, PYM1, MAG | KDM4E 2009/4885GAA 1492/4885POLB 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.