Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 7/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 2/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27185519 | 1.00 | STING1 (0.83) | STING1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL29784554 | 0.97 | STING1 (0.90) | STING1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL29784174 | 0.91 | STING1 (1.00) | STING1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL27185357 | 0.91 | STING1 (1.00) | STING1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL27185655 | 0.76 | STING1 (1.00) | STING1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL938487 | 0.74 | STING1 (0.44) | STING1LMNAKDM4EMAPT | |
| SCHEMBL19030768 | 0.74 | LMNA (0.72) | STING1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL29784402 | 0.73 | STING1 (0.82) | STING1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL27185737 | 0.73 | STING1 (0.82) | STING1LMNAKDM4EHSD17B10HPGD | |
| SCHEMBL29784480 | 0.71 | PARP1 (0.45) | STING1LMNAKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169921-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-08-11 | — | — | WO | disclosed |