Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 10/20 | 0.48 |
| ▸ | CES1 | P23141 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790426 | 0.79 | CES2 (0.56) | CES2CES1GAACYP2C19MEN1 | |
| SCHEMBL17485943 | 0.79 | CES2 (0.56) | CES2CES1GAACYP2C19MEN1 | |
| SCHEMBL12997589 | 0.73 | GAA (0.65) | CES2CES1GAACYP2C19MEN1 | |
| SCHEMBL4353902 | 0.73 | GAA (0.65) | CES2CES1GAACYP2C19MEN1 | |
| SCHEMBL7929793 | 0.72 | CES2 (0.50) | CES2CES1GAACYP2C19MEN1 | |
| Benzil SCHEMBL11427786 | 0.71 | CES2 (0.93) | CES2CES1CYP2C19MEN1KMT2A | |
| Benzil SCHEMBL16390243 | 0.71 | CES2 (0.93) | CES2CES1CYP2C19MEN1KMT2A | |
| Benzil SCHEMBL27353721 | 0.71 | CES2 (0.93) | CES2CES1CYP2C19MEN1KMT2A | |
| Benzil SCHEMBL2234045 | 0.69 | CES2 (0.88) | CES2CES1GAACYP2C19MEN1 | |
| SCHEMBL5597809 | 0.69 | CYP2C19 (0.54) | CES2CES1GAACYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110772506-B | Application of benzil hydrazone-1-naphthaldehyde Schiff base | 齐鲁工业大学 | 2022-07-22 | — | — | CN | disclosed |