SCHEMBL7790426

SCHEMBL7790426

NN=C(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 10/20 0.56
CES1 P23141 9/20 0.56
CYP2C19 P33261 2/20 0.52
GAA P10253 2/20 0.52
L3MBTL1 Q9Y468 3/20 0.46
TSHR P16473 2/20 0.46
POLB P06746 2/20 0.46
MAPT P10636 2/20 0.46
BLM P54132 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP3A4 P08684 1/20 0.46
PARP1 P09874 1/20 0.46
RECQL P46063 1/20 0.46
PMP22 Q01453 1/20 0.46
HSD17B10 Q99714 1/20 0.46
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17485943 1.00 CES2 (0.56) CES2CES1CYP2C19GAAL3MBTL1
SCHEMBL7929793 0.90 CES2 (0.50) CES2CES1CYP2C19GAACYP3A4
SCHEMBL5597810 0.84 CYP2C19 (0.54) CES2CES1CYP2C19GAAL3MBTL1
SCHEMBL5597809 0.84 CYP2C19 (0.54) CES2CES1CYP2C19GAAL3MBTL1
SCHEMBL18797319 0.83 CYP2C19 (0.50) CES2CES1CYP2C19GAAL3MBTL1
SCHEMBL20721103 0.83 CYP2C19 (0.50) CES2CES1CYP2C19GAAL3MBTL1
SCHEMBL28048938 0.80 MAPT (0.40) CES2CES1CYP2C19GAAL3MBTL1
SCHEMBL8532484 0.80 CES2 (0.52) CES2CES1CYP2C19GAAL3MBTL1
SCHEMBL29786173 0.79 CES2 (0.48) CES2CES1CYP2C19GAAL3MBTL1
SCHEMBL12997589 0.79 GAA (0.65) CES2CES1CYP2C19GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110790695-B Synthesis and application of benzil hydrazone-N-methyl-3-indole formaldehyde 齐鲁工业大学 2023-04-11 CN claimed
CN-110698383-B Structure, synthesis and application of benzil hydrazone-3-acetyl indole 齐鲁工业大学 2023-03-24 CN claimed
CN-110772506-B Application of benzil hydrazone-1-naphthaldehyde Schiff base 齐鲁工业大学 2022-07-22 CN claimed
CN-110790695-A Synthesis and application of benzil hydrazone-N-methyl-3-indole formaldehyde 齐鲁工业大学 2020-02-14 CN claimed
CN-110698383-A Structure, synthesis and application of benzil hydrazone-3-acetyl indole 齐鲁工业大学 2020-01-17 CN claimed
EP-0661357-B1 Polymeric pigment dispersants for use in coating compositions BASF CORP (US) 2001-10-31 EP claimed
EP-0661357-A2 Polymeric pigment dispersants for use in coating compositions BASF CORPORATION (US) 1995-07-05 EP claimed
US-5378762-A Functionalized acrylic copolymer with polyether and modified with hydrazide, hydrazone or oxime BASF CORPORATION (US) 1995-01-03 US claimed
JP-6128555-A None JP disclosed
CN-110790695-B Synthesis and application of benzil hydrazone-N-methyl-3-indole formaldehyde 齐鲁工业大学 2023-04-11 CN disclosed
CN-110790695-B Synthesis and application of benzil hydrazone-N-methyl-3-indole formaldehyde 齐鲁工业大学 2023-04-11 CN disclosed
CN-110698382-B Application of benzil hydrazone-3-indole formaldehyde Schiff base 齐鲁工业大学 2023-03-31 CN disclosed
CN-110698382-B Application of benzil hydrazone-3-indole formaldehyde Schiff base 齐鲁工业大学 2023-03-31 CN disclosed
CN-110698382-B Application of benzil hydrazone-3-indole formaldehyde Schiff base 齐鲁工业大学 2023-03-31 CN disclosed
EP-0038838-A4 SLEEVE FOR ATTACHMENT OF A CERAMIC DISK TO CYLINDRICAL SHAFT. GOODRICH CO B F (US) 1982-02-05 EP disclosed
EP-0038838-A1 SLEEVE FOR ATTACHMENT OF A CERAMIC DISK TO CYLINDRICAL SHAFT The B.F. GOODRICH Company (US) 1981-11-04 EP disclosed
WO-1981001132-A1 SLEEVE FOR ATTACHMENT OF A CERAMIC DISK TO CYLINDRICAL SHAFT GOODRICH CO B F (US) 1981-04-30 WO disclosed
US-4238490-A Antihypertensive pyridazin(2H)-3-ones DIAMOND SHAMROCK CORPORATION (US) 1980-12-09 US disclosed
EP-0018063-A1 Pyridazin (2H)-3-ones, process for their preparation and their use in antihypertensive agents DIAMOND SHAMROCK CORPORATION (US) 1980-10-29 EP disclosed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US disclosed