Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAT1 | O14929 | 10/20 | 0.54 |
| ▸ | EP300 | Q09472 | 10/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 3/20 | 0.46 |
| ▸ | CCNC | P24863 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454467 | 0.89 | USP30 (0.55) | HAT1EP300USP30MKNK1MKNK2 | |
| SCHEMBL30363245 | 0.87 | USP30 (0.54) | HAT1EP300USP30MKNK1MKNK2 | |
| Lithium Ion SCHEMBL31293538 | 0.85 | USP30 (0.53) | HAT1EP300USP30MKNK1MKNK2 | |
| SCHEMBL29786205 | 0.84 | USP30 (0.60) | HAT1EP300USP30PIK3CGCCNC | |
| SCHEMBL17452701 | 0.84 | HAT1 (0.54) | HAT1EP300USP30MKNK1MKNK2 | |
| SCHEMBL30998745 | 0.84 | USP30 (0.54) | HAT1EP300USP30MKNK1MKNK2 | |
| SCHEMBL20229576 | 0.84 | USP30 (0.52) | HAT1EP300USP30MKNK1MKNK2 | |
| SCHEMBL12683550 | 0.81 | JAK3 (0.51) | MKNK1MKNK2JAK3JAK1JAK2 | |
| SCHEMBL31212715 | 0.81 | USP30 (0.49) | HAT1EP300USP30PIK3CG | |
| SCHEMBL25416458 | 0.78 | PIK3CG (0.43) | HAT1EP300USP30MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939967-B | Pyrazolo [1,5-a ] pyridine compound, and preparation method and application thereof | 深圳众格生物科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-114787161-B | Pyrazolo [1,5-a ] pyridine compound, and preparation method and application thereof | 深圳众格生物科技有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-114787161-A | Pyrazolo [1,5-a ] pyridine compound and preparation method and application thereof | 深圳众格生物科技有限公司 | 2022-07-22 | — | — | CN | disclosed |