Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.54 |
| ▸ | HAT1 | O14929 | 10/20 | 0.48 |
| ▸ | EP300 | Q09472 | 10/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454467 | 0.86 | USP30 (0.55) | USP30HAT1EP300PIK3CGCHRM1 | |
| SCHEMBL31212715 | 0.86 | USP30 (0.49) | USP30HAT1EP300PIK3CGCHRM1 | |
| SCHEMBL30363245 | 0.85 | USP30 (0.54) | USP30HAT1EP300PIK3CGCHRM1 | |
| SCHEMBL29786205 | 0.84 | USP30 (0.60) | USP30HAT1EP300PIK3CGCHRM1 | |
| SCHEMBL29786187 | 0.84 | HAT1 (0.54) | USP30HAT1EP300PIK3CGMKNK1 | |
| SCHEMBL3321508 | 0.83 | SLC6A4 (0.47) | USP30NR4A2 | |
| SCHEMBL2059664 | 0.83 | BMP4 (0.47) | PIK3CGNR4A2MKNK2 | |
| Lithium Ion SCHEMBL31293538 | 0.83 | USP30 (0.53) | USP30HAT1EP300PIK3CGCHRM1 | |
| SCHEMBL17452701 | 0.82 | HAT1 (0.54) | USP30HAT1EP300PIK3CGCHRM1 | |
| SCHEMBL20229576 | 0.82 | USP30 (0.52) | USP30HAT1EP300PIK3CGCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |
| CN-112939967-B | Pyrazolo [1,5-a ] pyridine compound, and preparation method and application thereof | 深圳众格生物科技有限公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-114787161-B | Pyrazolo [1,5-a ] pyridine compound, and preparation method and application thereof | 深圳众格生物科技有限公司 | 2024-08-02 | — | — | CN | disclosed |