Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | ASPH | Q12797 | 2/20 | 0.36 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | AOC1 | P19801 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19568003 | 0.70 | RPS6KB1 (0.43) | JAK2JAK1KDM4CJAK3LRRK2 | |
| SCHEMBL2801895 | 0.70 | KDM4C (0.51) | GRM4UTS2RKDM4CASPHKDM8 | |
| SCHEMBL11392186 | 0.65 | NUDT1 (0.33) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL15415415 | 0.64 | KDM4C (0.34) | GRM4APPUTS2RJAK2JAK1 | |
| SCHEMBL6884915 | 0.63 | S1PR1 (0.52) | KDM4CASPHKDM8NPC1 | |
| SCHEMBL8054361 | 0.63 | IDH1 (0.46) | GRM4APPKDM4CASPHKDM8 | |
| SCHEMBL4612289 | 0.61 | GRM4 (0.38) | GRM4APPUTS2RJAK2JAK1 | |
| SCHEMBL23012182 | 0.61 | CCNB2 (0.32) | — | |
| SCHEMBL26326819 | 0.60 | NPC1 (0.56) | KDM4CASPHKDM8KDM4ERIOX2 | |
| SCHEMBL1679102 | 0.60 | ADH1B (0.59) | CHRM4CA2HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787161-A | Pyrazolo [1,5-a ] pyridine compound and preparation method and application thereof | 深圳众格生物科技有限公司 | 2022-07-22 | — | — | CN | disclosed |