SCHEMBL29786209

SCHEMBL29786209

CC(C)(C)[Si](C)(C)Oc1cc[nH]n1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.33
CA1 P00915 4/20 0.33
CA9 Q16790 4/20 0.33
PREP P48147 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21465416 0.81
SCHEMBL31074635 0.74 DUT (0.40) CA12CA1CA9
SCHEMBL4278388 0.71
SCHEMBL21468555 0.71
SCHEMBL20029088 0.68 DUT (0.35)
SCHEMBL6763899 0.67 PREP (0.53) CA12CA1CA9PREP
SCHEMBL875297 0.67
SCHEMBL17648445 0.67 NUDT1 (0.46)
SCHEMBL18338551 0.66 DUT (0.31)
SCHEMBL28724031 0.65 KDM4E (0.39) CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114787161-A Pyrazolo [1,5-a ] pyridine compound and preparation method and application thereof 深圳众格生物科技有限公司 2022-07-22 CN disclosed