Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668085 | 1.00 | ABCB1 (0.38) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2684734 | 1.00 | ABCB1 (0.38) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29684755 | 1.00 | ABCB1 (0.38) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29684694 | 0.94 | ABCB1 (0.39) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL667409 | 0.94 | ABCB1 (0.39) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15465916 | 0.93 | TAS1R3 (0.33) | ALDH1A1HPGDSMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL2683648 | 0.91 | ABCB1 (0.36) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29684859 | 0.91 | ABCB1 (0.36) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL668634 | 0.91 | ABCB1 (0.36) | ABCB1CYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL667491 | 0.89 | PLK1 (0.35) | ABCB1ALDH1A1HPGDSMN1; SMN2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357904-B1 | CHIRAL DIACHYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | PRECIGEN INC (US) | 2022-07-06 | — | — | EP | disclosed |