Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147915 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4923713 | 0.90 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL4923704 | 0.90 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2993486 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL2993484 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL10220038 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11300020 | 0.79 | GAA (0.74) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL12838364 | 0.79 | GAA (0.74) | SMN1; SMN2ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL4554291 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL25041334 | 0.77 | ESRRG (0.69) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357904-B1 | CHIRAL DIACHYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | PRECIGEN INC (US) | 2022-07-06 | — | — | EP | disclosed |