Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993486 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2USP2RAB9AMAPTGAA | |
| SCHEMBL4923713 | 0.90 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL4923704 | 0.90 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL2987972 | 0.86 | MAPT (0.59) | SMN1; SMN2USP2RAB9AMAPTGAA | |
| SCHEMBL29786246 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTGAAALDH1A1KMT2A | |
| SCHEMBL10147915 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTGAAALDH1A1KMT2A | |
| SCHEMBL10220038 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL2995787 | 0.80 | GAA (0.70) | USP2RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL2995788 | 0.80 | GAA (0.70) | USP2RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL3000116 | 0.77 | POLB (0.58) | USP2MAPTGAAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184811-A1 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | BRIDGE BIORESEARCH RIGHTS (JERSEY) LIMITED (GB) | 2010-07-22 | — | — | US | disclosed |
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184811-A1 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | ODC1, OTC, ACACB | SMN1; SMN2 4448/4885USP2 3612/4885RAB9A 4462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.