Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29786337 | 0.87 | HIF1A (0.46) | HIF1AMEN1KMT2ANPC1ASAH1 | |
| SCHEMBL29786331 | 0.84 | HIF1A (0.46) | HIF1AMEN1KMT2ANPC1ASAH1 | |
| SCHEMBL29786257 | 0.81 | HPGD (0.44) | HIF1AMEN1KMT2ANPC1ASAH1 | |
| SCHEMBL24810745 | 0.81 | ASAH1 (0.49) | NPC1ASAH1SMN1; SMN2TAAR1RAB9A | |
| SCHEMBL29786260 | 0.79 | MCHR1 (0.45) | HIF1AMEN1KMT2ALMNAASAH1 | |
| SCHEMBL24811055 | 0.78 | HIF1A (0.44) | HIF1AMEN1KMT2ALMNANPC1 | |
| SCHEMBL29786381 | 0.75 | ASAH1 (0.39) | HIF1AMEN1KMT2ANPC1ASAH1 | |
| SCHEMBL24809464 | 0.74 | ASAH1 (0.56) | ASAH1 | |
| SCHEMBL24810685 | 0.74 | ASAH1 (0.58) | ASAH1 | |
| SCHEMBL29003728 | 0.73 | RAB9A (0.47) | NPC1ASAH1SMN1; SMN2RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787135-A | Substituted imidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |