Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29786260 | 0.87 | MCHR1 (0.45) | ASAH1MAPTRXFP1RAB9AALDH1A1 | |
| SCHEMBL29817652 | 0.79 | FAAH (0.39) | ASAH1DYRK1AWNT1RAB9AALDH1A1 | |
| SCHEMBL24809696 | 0.79 | FAAH (0.39) | ASAH1DYRK1AWNT1RAB9AALDH1A1 | |
| SCHEMBL29786337 | 0.78 | HIF1A (0.46) | ASAH1MAPTRXFP1RAB9AALDH1A1 | |
| SCHEMBL29786310 | 0.77 | ASAH1 (0.41) | ASAH1MAPTRXFP1RAB9AALDH1A1 | |
| SCHEMBL29786331 | 0.75 | HIF1A (0.46) | ASAH1MAPTRXFP1RAB9AALDH1A1 | |
| SCHEMBL29786257 | 0.75 | HPGD (0.44) | ASAH1MAPTRXFP1RAB9AALDH1A1 | |
| SCHEMBL29786281 | 0.75 | HIF1A (0.43) | ASAH1MAPTRXFP1RAB9AALDH1A1 | |
| SCHEMBL29003728 | 0.70 | RAB9A (0.47) | ASAH1MAPTRXFP1RAB9AALDH1A1 | |
| SCHEMBL24810745 | 0.69 | ASAH1 (0.49) | ASAH1MAPTRAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787135-A | Substituted imidazole carboxamides and their use in the treatment of medical disorders | 比亚尔R&D投资股份公司 | 2022-07-22 | — | — | CN | disclosed |