SCHEMBL29787355

SCHEMBL29787355

CCN(CC)c1ccc2nc3c4cccnc4c(=O)cc-3oc2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.74
KMT2A Q03164 6/20 0.74
NPC1 O15118 2/20 0.74
RAB9A P51151 2/20 0.74
POLB P06746 1/20 0.74
SCP2 P22307 1/20 0.55
GPR84 Q9NQS5 10/20 0.41
ALDH1A1 P00352 7/20 0.41
KDM4E B2RXH2 5/20 0.41
GLA P06280 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
MAPT P10636 5/20 0.40
CASP1 P29466 2/20 0.40
CASP7 P55210 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 1/20 0.40
ALOX15 P16050 1/20 0.40
MPI P34949 1/20 0.40
BRCA1 P38398 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28788676 1.00 MEN1 (0.74) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL16696323 0.88 KMT2A (0.63) MEN1KMT2ANPC1RAB9APOLB
Nile Red SCHEMBL29373685 0.85 MEN1 (1.00) MEN1KMT2ANPC1RAB9APOLB
Nile Red SCHEMBL49047 0.85 MEN1 (1.00) MEN1KMT2ANPC1RAB9APOLB
Nile Red SCHEMBL28703996 0.83 MEN1 (0.93) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL7159065 0.78 MEN1 (0.70) MEN1KMT2ANPC1RAB9APOLB
Nile Blue SCHEMBL29356294 0.78 MEN1 (0.77) MEN1KMT2ANPC1RAB9APOLB
Nile Blue SCHEMBL12393690 0.78 MEN1 (0.77) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL56792 0.77 MEN1 (0.76) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL4664437 0.77 MEN1 (0.76) MEN1KMT2ANPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773361-B N-heteronile erythronium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2023-04-11 CN claimed
CN-114773361-A N-heteronile erythronium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2022-07-22 CN claimed
CN-114773361-B N-heteronile erythronium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2023-04-11 CN disclosed
CN-114773361-A N-heteronile erythronium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2022-07-22 CN disclosed