Sugi Predict

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Nile Blue

Nile Blue

SCHEMBL12393690

CCN(CC)c1ccc2nc3c4ccccc4c(=N)cc-3oc2c1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 10/20 0.77
▸ KMT2A Q03164 10/20 0.77
▸ NPC1 O15118 5/20 0.77
▸ RAB9A P51151 4/20 0.77
▸ POLB P06746 3/20 0.77
▸ SCP2 P22307 1/20 0.48
▸ ALDH1A1 P00352 8/20 0.40
▸ KDM4E B2RXH2 6/20 0.40
▸ L3MBTL1 Q9Y468 5/20 0.40
▸ GLA P06280 3/20 0.40
▸ TERT O14746 1/20 0.39
▸ MAPT P10636 9/20 0.39
▸ CASP1 P29466 4/20 0.39
▸ CASP7 P55210 4/20 0.39
▸ HTT P42858 4/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ TP53 P04637 2/20 0.39
▸ BRCA1 P38398 2/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ MPI P34949 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nile Blue SCHEMBL29356294 1.00 MEN1 (0.77) MEN1KMT2ANPC1RAB9APOLB
Nile Blue SCHEMBL4051129 0.93 MEN1 (0.71) MEN1KMT2ANPC1RAB9APOLB
Nile Blue SCHEMBL4051132 0.93 MEN1 (0.71) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL18070239 0.87 MEN1 (0.62) MEN1KMT2ANPC1RAB9APOLB
Nile Red SCHEMBL29373685 0.87 MEN1 (1.00) MEN1KMT2ANPC1RAB9APOLB
Nile Red SCHEMBL49047 0.87 MEN1 (1.00) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL22372426 0.87 MEN1 (0.75) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL23733292 0.86 MEN1 (0.58) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL16696324 0.86 MEN1 (0.61) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL16696323 0.85 KMT2A (0.63) MEN1KMT2ANPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250283875-A1 SYSTEMS AND METHODS FOR ENHANCED DETECTION AND QUANTIFICATION OF ANALYTES SIRO DIAGNOSTICS, INC. 2025-09-11 — — US disclosed
US-12320803-B2 Systems and methods for enhanced detection and quantification of analytes SIRO DIAGNOSTICS, INC. (US) 2025-06-03 — — US disclosed
US-20230190761-A1 METHYLENE BLUE STABILIZED MRNA COMPOSITIONS MODERNATX, INC. (US) 2023-06-22 — — US disclosed
US-20220387631-A1 NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 — — US disclosed
WO-2022106898-A1 FLUORESCENT POLYMERS AND SOLUTIONS THEREOF FOR SCALE CONTROL IN AQUEOUS SYSTEMS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-05-27 — — WO disclosed
WO-2022109274-A1 FLUORESCENT POLYMERS AND SOLUTIONS THEREOF FOR SCALE CONTROL IN AQUEOUS SYSTEMS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-05-27 — — WO disclosed
US-20220155290-A1 SYSTEMS AND METHODS FOR ENHANCED DETECTION AND QUANTIFICATION OF ANALYTES CUE HEALTH INC. (US) 2022-05-19 — — US disclosed
US-11237161-B2 Systems and methods for enhanced detection and quantification of analytes CUE HEALTH INC. (US) 2022-02-01 — — US disclosed
US-11229649-B2 Methods for treating cryptosporidiosis using triazolopyridazines UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2022-01-25 — — US disclosed
WO-2021237084-A1 METHYLENE BLUE STABILIZED MRNA COMPOSITIONS MODERNATX, INC. (US) 2021-11-25 — — WO disclosed
US-8362447-B2 Degradable taggant and method of making and using thereof WORCESTER POLYTECHNIC INSTITUTE (US) 2013-01-29 — — US disclosed
US-8003767-B2 Sulfonated [8,9]benzophenoxazine dyes and the use of their labelled conjugates APPLIED BIOSYSTEMS, LLC (US) 2011-08-23 — — US disclosed
EP-2325649-A1 Dye-assisted laser desorption ionization (DALDI) Centre National de la Recherche Scientifique (CNRS) (FR) 2011-05-25 — — EP disclosed
US-20100288943-A1 DEGRADABLE TAGGANT AND METHOD OF MAKING AND USING THEREOF WORCESTER POLYTECHNIC INSTITUTE (US) 2010-11-18 — — US disclosed
US-20100288943-A1 DEGRADABLE TAGGANT AND METHOD OF MAKING AND USING THEREOF WORCESTER POLYTECHNIC INSTITUTE (US) 2010-11-18 — — US disclosed
US-20100059740-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2010-03-11 — — US disclosed
WO-2009023287-A1 POLYMERIZED NILE BLUE DERIVATIVES FOR PLASTICIZER-FREE FLUORESCENT ION OPTODE MICROSPHERE SENSORS BECKMAN COULTER, INC. (US) 2009-02-19 — — WO disclosed
US-20090004653-A1 Sulfonated [8,9]benzophenoxazine dyes and the use of their labelled conjugates APPLERA CORPORATION 2009-01-01 — — US disclosed
WO-2008087031-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2008-07-24 — — WO disclosed
US-7238789-B2 Sulfonated [8,9] benzophenoxazine dyes and the use of their labelled conjugates APPLERA CORPORATION (US) 2007-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11229649-B2 Methods for treating cryptosporidiosis using triazolopyridazines CLPP, SI, SAMHD1 MEN1 4574/4885KMT2A 3111/4885NPC1 1706/4885
US-20220387631-A1 NEAR-INFRARED FLUORESCENT CONTRAST BIOIMAGING AGENTS AND METHODS OF USE THEREOF CD68, MSR1, CD47 MEN1 498/4885KMT2A 4412/4885NPC1 363/4885
US-20230190761-A1 METHYLENE BLUE STABILIZED MRNA COMPOSITIONS LMNB2, NSUN2, RNMT MEN1 1380/4885KMT2A 93/4885NPC1 453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.