Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596594 | 1.00 | MEN1 (0.43) | MEN1KMT2ANPSR1CYP3A4TSHR | |
| SCHEMBL14627743 | 0.90 | SMN1; SMN2 (0.42) | MEN1KMT2ABTN3A1NPC1RAB9A | |
| SCHEMBL12621322 | 0.88 | BTN3A1 (0.41) | MEN1KMT2ANPSR1BTN3A1RECQL | |
| SCHEMBL21023979 | 0.88 | BTN3A1 (0.41) | MEN1KMT2ANPSR1BTN3A1RECQL | |
| SCHEMBL12621315 | 0.87 | TSHR (0.44) | MEN1KMT2ATSHRBTN3A1RECQL | |
| SCHEMBL13242487 | 0.87 | ALDH1A1 (0.42) | MEN1KMT2ANPSR1BTN3A1RAB9A | |
| SCHEMBL12248659 | 0.87 | ALDH1A1 (0.42) | MEN1KMT2ANPSR1BTN3A1RAB9A | |
| SCHEMBL23992574 | 0.87 | BTN3A1 (0.53) | MEN1KMT2ANPSR1BTN3A1MAPT | |
| SCHEMBL800889 | 0.87 | BTN3A1 (0.53) | MEN1KMT2ANPSR1BTN3A1MAPT | |
| SCHEMBL25387275 | 0.87 | BTN3A1 (0.53) | MEN1KMT2ANPSR1BTN3A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112442011-B | Prodrug compound and application thereof in treating cancers | 润佳（苏州）医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-4021912-A1 | PRODRUGS OF THE TYROSINE KINASE INHIBITOR FOR TREATING CANCER | Risen (Suzhou) Pharma Tech Co., Ltd. (CN) | 2022-07-06 | — | — | EP | disclosed |