SCHEMBL800889

SCHEMBL800889

COC(=O)[C@H](C)NP(=O)(Cl)Oc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 10/20 0.53
MAPK1 P28482 1/20 0.45
ANPEP P15144 1/20 0.42
LAP3 P28838 1/20 0.42
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MEN1 O00255 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ELANE P08246 1/20 0.41
SRC P12931 1/20 0.41
KDM1A O60341 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23992574 1.00 BTN3A1 (0.53) BTN3A1MAPK1ANPEPLAP3KMT2A
SCHEMBL12870471 1.00 BTN3A1 (0.53) BTN3A1MAPK1ANPEPLAP3KMT2A
SCHEMBL25387275 1.00 BTN3A1 (0.53) BTN3A1MAPK1ANPEPLAP3KMT2A
SCHEMBL20248041 0.88 BTN3A1 (0.55) BTN3A1ANPEPLAP3KMT2AMEN1
SCHEMBL524066 0.88 BTN3A1 (0.55) BTN3A1ANPEPLAP3KMT2AMEN1
SCHEMBL15588619 0.88 BTN3A1 (0.55) BTN3A1ANPEPLAP3KMT2AMEN1
SCHEMBL524067 0.88 BTN3A1 (0.55) BTN3A1ANPEPLAP3KMT2AMEN1
SCHEMBL16374214 0.88 BTN3A1 (0.55) BTN3A1ANPEPLAP3KMT2AMEN1
SCHEMBL14627743 0.88 SMN1; SMN2 (0.42) BTN3A1KMT2AMEN1
SCHEMBL20773105 0.88 ANPEP (0.44) BTN3A1ANPEPLAP3KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129112-A1 Novel Prodrugs Derived from Nicotinic Acid and Ribose MITOPOWER, INC. 2025-04-24 US disclosed
US-20250057867-A1 NUCLEOSIDE PHOSPHORAMIDATES GILEAD SCIENCES INC (US) 2025-02-20 US disclosed
US-12168673-B2 Prodrugs derived from nicotinic acid and ribose MITOPOWER, INC. (US) 2024-12-17 US disclosed
EP-4463158-A2 NOVEL PRODRUGS DERIVED FROM NICOTINIC ACID AND RIBOSE Mitopower, Inc. (US) 2024-11-20 EP disclosed
CN-118922189-A Novel prodrugs derived from niacin and ribose 线粒体能量有限公司 2024-11-08 CN disclosed
CN-114008058-B Prodrugs of CDK inhibitors for the treatment of cancer 润佳(苏州)医药科技有限公司 2024-07-05 CN disclosed
CN-117362276-A Tropomyosin receptor kinase A inhibitor and preparation method and application thereof 复旦大学 2024-01-09 CN disclosed
EP-4282482-A2 Nucleoside phosphoramidate prodrugs Gilead Sciences, Inc. (US) 2023-11-29 EP disclosed
CN-111848579-B Prodrugs of 4- (2, 6-dichlorobenzoylamino) -N- (4-piperidinyl) -1H-pyrazole-3-carboxamide 君实润佳(上海)医药科技有限公司 2023-11-14 CN disclosed
US-20230279035-A1 Novel Prodrugs Derived from Nicotinic Acid and Ribose MITOPOWER, INC. 2023-09-07 US disclosed
WO-2009142827-A2 COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRAL INFECTION GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2009-11-26 WO disclosed
US-7601703-B2 Enzyme catalyzed therapeutic agents CELMED ONCOLOGY (USA), INC. (CA) 2009-10-13 US disclosed
EP-1709056-B1 PHOSPHORAMIDATE DERIVATIVES UNIV CARDIFF (GB) 2009-06-17 EP disclosed
US-20090069268-A1 NOVEL PHOSPHORAMIDATE COMPOUNDS AND METHODS OF USE CELMED ONCOLOGY (USA), INC. 2009-03-12 US disclosed
WO-2008121634-A2 NUCLEOSIDE PHOSPHORAMIDATE PRODRUGS PHARMASSET, INC. (US) 2008-10-09 WO disclosed
US-20070275910-A1 Phosphoramidate Derivatives UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2007-11-29 US disclosed
US-20070275910-A1 Phosphoramidate Derivatives UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) 2007-11-29 US disclosed
US-20070265222-A1 Nucleoside Aryl Phosphoramidates for the Treatment of Rna-Dependent Rna Viral Infection MERCK SHARP & DOHME CORP. 2007-11-15 US disclosed
US-20070265222-A1 Nucleoside Aryl Phosphoramidates for the Treatment of Rna-Dependent Rna Viral Infection MERCK SHARP & DOHME CORP. 2007-11-15 US disclosed
US-20070213307-A1 Methods to treat autoimmune and inflammatory conditions CELMED ONCOLOGY (USA), INC. 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090069268-A1 NOVEL PHOSPHORAMIDATE COMPOUNDS AND METHODS OF USE MTAP, TYMP, INPP5D BTN3A1 2388/4885MAPK1 1656/4885ANPEP 864/4885
US-20250129112-A1 Novel Prodrugs Derived from Nicotinic Acid and Ribose NME4, NADK, NNT BTN3A1 3722/4885MAPK1 3800/4885ANPEP 2505/4885
US-20250057867-A1 NUCLEOSIDE PHOSPHORAMIDATES PNP, RNGTT, NSUN2 BTN3A1 3601/4885MAPK1 2200/4885ANPEP 359/4885
US-20230279035-A1 Novel Prodrugs Derived from Nicotinic Acid and Ribose NME4, NADK, NAMPT BTN3A1 4110/4885MAPK1 3890/4885ANPEP 2873/4885
US-20070265222-A1 Nucleoside Aryl Phosphoramidates for the Treatment of Rna-Dependent Rna Viral Infection NSUN3, NSUN2, PNP BTN3A1 3346/4885MAPK1 2526/4885ANPEP 281/4885
US-12168673-B2 Prodrugs derived from nicotinic acid and ribose NNT, NME4, NADK BTN3A1 4010/4885MAPK1 3878/4885ANPEP 2319/4885
US-20070213307-A1 Methods to treat autoimmune and inflammatory conditions SSB, ENPP2, TPMT BTN3A1 1069/4885MAPK1 3195/4885ANPEP 1862/4885
US-20070275910-A1 Phosphoramidate Derivatives HRH4, HRH3, NR1H4 BTN3A1 2425/4885MAPK1 1925/4885ANPEP 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.