Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 13/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24596313 | 1.00 | MAT2A (0.47) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596155 | 0.90 | MAT2A (0.47) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30611291 | 0.88 | PDE4A (0.52) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596154 | 0.88 | PDE4A (0.52) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30649297 | 0.86 | MAT2A (0.45) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596165 | 0.86 | MAT2A (0.45) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29790059 | 0.84 | MAT2A (0.48) | MAT2A | |
| SCHEMBL24596356 | 0.84 | MAT2A (0.67) | MAT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24596333 | 0.84 | MAT2A (0.48) | MAT2A | |
| SCHEMBL29789919 | 0.84 | MAT2A (0.67) | MAT2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143864-A1 | TRICYCLIC COMPOUND AND USE THEREOF | 江苏先声药业有限公司 | 2022-07-07 | — | — | WO | disclosed |