Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653141 | 0.75 | ALDH1A1 (0.61) | ALDH1A1RBBP9L3MBTL1PLA2G4ANPC1 | |
| SCHEMBL29529044 | 0.74 | ALDH1A1 (0.47) | ALDH1A1RBBP9ALPLALPIALPG | |
| SCHEMBL13017814 | 0.72 | ALDH1A1 (0.40) | ALDH1A1RBBP9CACNA2D1ALPLALPI | |
| SCHEMBL31098537 | 0.70 | ALDH1A1 (0.46) | ALDH1A1CNR2PTGIRL3MBTL1NPC1 | |
| SCHEMBL29776070 | 0.70 | PLAT (0.38) | CNR2PTGIRNPC1GAARAB9A | |
| SCHEMBL223969 | 0.69 | ALDH1A1 (0.53) | ALDH1A1RBBP9L3MBTL1PLA2G4ANPC1 | |
| SCHEMBL11161156 | 0.68 | ALDH1A1 (0.56) | ALDH1A1RBBP9L3MBTL1PLA2G4AKMT2A | |
| SCHEMBL13846199 | 0.68 | PLAT (0.37) | CNR2NPC1GAARAB9AKMT2A | |
| SCHEMBL15400307 | 0.66 | ALDH1A1 (0.53) | ALDH1A1RBBP9EPHX2PLA2G4ANPC1 | |
| SCHEMBL12751157 | 0.66 | ACHE (0.51) | PTGIRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-B | Inhibitors of WDR5 protein-protein binding | 普罗佩纶治疗公司 | 2022-07-26 | — | — | CN | disclosed |