Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22230710 | 0.81 | PDE4D (0.51) | ALDH1A1GAAKDM4ENPSR1CA12 | |
| SCHEMBL3406573 | 0.78 | ALDH1A1 (0.47) | ALDH1A1GAAKDM4ENPSR1L3MBTL1 | |
| SCHEMBL29790182 | 0.78 | L3MBTL1 (0.38) | ALDH1A1KDM4EL3MBTL1HPGDKMT2A | |
| SCHEMBL11698989 | 0.77 | ALDH1A1 (0.49) | ALDH1A1GAAKDM4ENPSR1HPGD | |
| SCHEMBL3401357 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4ENPSR1L3MBTL1 | |
| SCHEMBL1527647 | 0.73 | KMT2A (0.44) | ALDH1A1GAANPSR1L3MBTL1HPGD | |
| SCHEMBL3163791 | 0.73 | ALDH1A1 (0.45) | ALDH1A1GAAKDM4EL3MBTL1HPGD | |
| SCHEMBL3404681 | 0.72 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4ENPSR1L3MBTL1 | |
| SCHEMBL9278011 | 0.71 | KDM4E (0.48) | ALDH1A1KDM4ENPSR1L3MBTL1HPGD | |
| SCHEMBL28828745 | 0.69 | KDM4E (0.49) | ALDH1A1GAAKDM4ENPSR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022174883-A1 | 5-MEMBERED HETEROCYCLYL DERIVATIVES AS DUAL LPA RECEPTOR 1 AND LPA RECEPTOR 2 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-08-25 | — | — | WO | disclosed |