Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331962 | 0.98 | TSHR (0.48) | TSHRALDH1A1THRBMGAMGAA | |
| SCHEMBL7648165 | 0.91 | TSHR (0.48) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL6463788 | 0.88 | TSHR (0.50) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL26700384 | 0.86 | TSHR (0.40) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL16448991 | 0.86 | TSHR (0.40) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL12015626 | 0.86 | TSHR (0.40) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL195069 | 0.85 | — | — | |
| SCHEMBL5049754 | 0.84 | TSHR (0.42) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL31672720 | 0.84 | TSHR (0.42) | TSHRALDH1A1MGAMGAASI | |
| SCHEMBL30179205 | 0.84 | TSHR (0.42) | TSHRALDH1A1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114787159-A | BRM targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-07-22 | — | — | CN | disclosed |