Sugi Predict

Sugi Predict / Compounds / SCHEMBL5049754

SCHEMBL5049754

SCHEMBL5049754

COCCOCCOCC(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 6/20 0.42
▸ HSD17B10 Q99714 1/20 0.39
▸ MGAM O43451 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ SI P14410 1/20 0.39
▸ MGAM2 Q2M2H8 1/20 0.39
▸ CA2 P00918 1/20 0.35
▸ NAMPT P43490 1/20 0.35
▸ ABCB11 O95342 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ ADRA2B P18089 1/20 0.34
▸ OPRD1 P41143 1/20 0.34
▸ SCN5A Q14524 1/20 0.34
▸ EPHX2 P34913 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ LMNA P02545 1/20 0.33
▸ TET2 Q6N021 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16917910 1.00 TSHR (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL15360069 1.00 TSHR (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL31672720 1.00 TSHR (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL30179205 1.00 TSHR (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL518145 0.98 TSHR (0.43) TSHRHSD17B10MGAMGAASI
SCHEMBL7648165 0.93 TSHR (0.48) TSHRHSD17B10MGAMGAASI
SCHEMBL6463788 0.90 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL28565203 0.86 CA2 (0.35) TSHRCA2NAMPTABCB11CYP3A4
SCHEMBL8390474 0.86 CA2 (0.35) TSHRCA2NAMPTABCB11CYP3A4
SCHEMBL14193699 0.85 MGAM (0.39) TSHRHSD17B10MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069648-A Long-acting preparation of amide local anesthetic based on prodrug technology 南通大学 2023-11-17 — — CN claimed
US-5700316-A COMPRISED OF COLORANT AND VEHICLE OF POLY(ALKYLENE OXIDE) ALKYLATE OR DIALKYLATE OR POLYOXA-ALKANOIC ESTER OR DIESTER XEROX CORPORATION (US) 1997-12-23 — — US claimed
CN-117069648-A Long-acting preparation of amide local anesthetic based on prodrug technology 南通大学 2023-11-17 — — CN disclosed
US-20230357631-A1 CURABLE COMPOSITION, CURED FILM PRODUCED USING SAME, AND COLOR FILTER COMPRISING SAME SAMSUNG SDI CO., LTD. (KR) 2023-11-09 — — US disclosed
CN-116891465-A N-substituted quinolinone compounds, preparation method and application thereof 苏州旺山旺水生物医药有限公司 2023-10-17 — — CN disclosed
WO-2023186023-A1 N-SUBSTITUTED QUINOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州旺山旺水生物医药股份有限公司 2023-10-05 — — WO disclosed
US-9085587-B2 Inhibitors of hepatitis C virus PRESIDIO PHARMACEUTICALS, INC. (US) 2015-07-21 — — US disclosed
WO-2013163466-A1 INHIBITORS OF HEPATITIS C VIRUS PRESIDIO PHARMACEUTICALS, INC. (US) 2013-10-31 — — WO disclosed
US-7905948-B2 Phase change ink compositions XEROX CORPORATION (US) 2011-03-15 — — US disclosed
US-7875698-B2 comprising dendritic polymer core of hyperbranched polyglycidol; for use in radiation curable varnishes, lacquers, printing inks, and inkjet inks AGFA GRAPHICS NV (BE) 2011-01-25 — — US disclosed
US-7795324-B2 Radiation curable compositions AGFA GRAPHICS, N.V. (BE) 2010-09-14 — — US disclosed
US-20070167606-A1 Polyethylene glycol aldehydes WON CHEE-YOUB 2007-07-19 — — US disclosed
US-7211679-B2 Perfluoroether acyl oligothiophene compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-01 — — US disclosed
US-7151276-B2 Semiconductors containing perfluoroether acyl oligothiophene compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-12-19 — — US disclosed
WO-2006098859-A1 SEMICONDUCTORS CONTAINING PERFLUOROETHER ACYL OLIGOTHIOPHENE COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-09-21 — — WO disclosed
US-20060202191-A1 Semiconductors containing perfluoroether acyl oligothiohpene compounds 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 — — US disclosed
US-20060205172-A1 Perfluoroether acyl oligothiophene compounds 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 — — US disclosed
US-6749988-B2 PREVENTING A RESIST FILM FROM THINNING AND ALSO FOR ENHANCING THE RESOLUTION AND FOCUS MARGIN OF RESIST; HETEROCYCLIC AMINE COMPOUNDS HAVING A HYDRATING GROUP SUCH AS A HYDROXY, ETHER, ESTER, CARBONYL, CARBONATE GROUP OR LACTONE RING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-06-15 — — US disclosed
US-20020098443-A1 Amine compounds, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-07-25 — — US disclosed
US-5700316-A COMPRISED OF COLORANT AND VEHICLE OF POLY(ALKYLENE OXIDE) ALKYLATE OR DIALKYLATE OR POLYOXA-ALKANOIC ESTER OR DIESTER XEROX CORPORATION (US) 1997-12-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020098443-A1 Amine compounds, resist compositions and patterning process PARG, EHMT1, EHMT2 TSHR 3757/4885HSD17B10 1747/4885MGAM 1619/4885
US-20070167606-A1 Polyethylene glycol aldehydes ALDH2, ADH5, ADH1A TSHR 4360/4885HSD17B10 85/4885MGAM 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.