Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22762634 | 0.79 | LMNA (0.36) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL29566134 | 0.78 | CTPS1 (0.69) | CTPS1 | |
| SCHEMBL22762643 | 0.78 | CTPS1 (0.69) | CTPS1 | |
| SCHEMBL22749305 | 0.72 | LMNA (0.36) | MEN1NPC1RAB9AKMT2APLK4 | |
| SCHEMBL21392085 | 0.71 | FFAR4 (0.35) | MEN1NPC1RAB9AKMT2AMAPK13 | |
| Hydrochloric Acid SCHEMBL29368124 | 0.71 | LMNA (0.35) | MEN1NPC1RAB9AKMT2AMAPK13 | |
| Hydrochloric Acid SCHEMBL28701070 | 0.71 | LMNA (0.35) | MEN1NPC1RAB9AKMT2AMAPK13 | |
| SCHEMBL22758556 | 0.70 | FFAR4 (0.39) | MEN1KMT2AMAPK14ALDH1A1MAPT | |
| Lithium SCHEMBL30725900 | 0.69 | FFAR4 (0.38) | MEN1KMT2AMAPK14ALDH1A1MAPT | |
| SCHEMBL29142075 | 0.69 | FFAR4 (0.38) | MEN1KMT2AMAPK14ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041715-A1 | SULFONAMIDE INHIBITORS AS CTPS 1 INHIBITORS | Step Pharma S.A.S. (FR) | 2022-08-17 | — | — | EP | disclosed |