Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22758556 | 0.99 | FFAR4 (0.39) | FFAR4ALDH1A1ALOX5PDE5AALOX15 | |
| SCHEMBL29142075 | 0.97 | FFAR4 (0.38) | FFAR4ALDH1A1ALOX5PDE5AALOX15 | |
| Lithium Ion SCHEMBL22749301 | 0.86 | FFAR4 (0.35) | FFAR4ALDH1A1ALOX5ALOX15MAPK14 | |
| SCHEMBL21392151 | 0.85 | FFAR4 (0.37) | FFAR4ALDH1A1ALOX5ALOX15MAPK14 | |
| SCHEMBL21410121 | 0.78 | MAP4K4 (0.40) | ALDH1A1PDE5AMAP4K4MAPK14LMNA | |
| SCHEMBL22749305 | 0.76 | LMNA (0.36) | FFAR4ALDH1A1MAPK14LMNAGAA | |
| SCHEMBL28682801 | 0.76 | FFAR4 (0.36) | FFAR4ALDH1A1ALOX5ALOX15MAPK14 | |
| SCHEMBL21392085 | 0.76 | FFAR4 (0.35) | FFAR4ALDH1A1ALOX5ALOX15MAPK14 | |
| SCHEMBL22762634 | 0.76 | LMNA (0.36) | FFAR4ALDH1A1ALOX5ALOX15MAPK14 | |
| Hydrochloric Acid SCHEMBL29368124 | 0.75 | LMNA (0.35) | FFAR4ALDH1A1MAPK14LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008039-B | Compounds as human CTPS1 inhibitors for the treatment of proliferative diseases | 斯泰普制药股份公司 | 2024-01-16 | — | — | CN | disclosed |