SCHEMBL29791995

SCHEMBL29791995

OC(c1ccc(F)cc1C(F)(F)F)c1cnc2cnccn12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 6/20 0.34
KIT P10721 2/20 0.34
TRPC5 Q9UL62 2/20 0.32
CYP17A1 P05093 1/20 0.31
DDR2 Q16832 2/20 0.31
ABL1 P00519 1/20 0.31
BCR P11274 1/20 0.31
CYP3A4 P08684 1/20 0.31
DPP4 P27487 1/20 0.31
F2RL1 P55085 4/20 0.31
PRKD3 O94806 1/20 0.31
MAP4K4 O95819 1/20 0.31
MATK P42679 1/20 0.31
MAPK8 P45983 1/20 0.31
MAPK9 P45984 1/20 0.31
CSNK1A1 P48729 1/20 0.31
CSNK1D P48730 1/20 0.31
LIMK1 P53667 1/20 0.31
CSNK1G2 P78368 1/20 0.31
TAOK1 Q7L7X3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24177150 1.00 DDR1 (0.34) DDR1KITTRPC5CYP17A1DDR2
SCHEMBL24176775 0.91 CYP3A4 (0.33) DDR1KITTRPC5DDR2ABL1
SCHEMBL26019981 0.87 DDR1 (0.35) DDR1KITDDR2ABL1BCR
SCHEMBL24176722 0.87 ADRA2C (0.34) DDR1KITDDR2CYP3A4
SCHEMBL24176749 0.84 LIMK1 (0.39) DDR1KITDDR2ABL1BCR
SCHEMBL24176794 0.84 CYP1A2 (0.39) DDR1KITCYP3A4CLK4
SCHEMBL26019953 0.83 F2RL1 (0.32) F2RL1CCR5
SCHEMBL24176773 0.79 DDR1 (0.39) DDR1KITDDR2ABL1BCR
SCHEMBL26019925 0.76 TNK2 (0.36)
SCHEMBL26019904 0.74 DDR1 (0.33) DDR1DDR2F2RL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624041-B2 Heterocyclic compound and use thereof WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2026-05-12 US disclosed
CN-114907408-B Heterocyclic compound, intermediate thereof, preparation method and application thereof 武汉朗来科技发展有限公司 2024-05-03 CN disclosed
CN-113880843-B Heterocyclic compound and application thereof 武汉朗来科技发展有限公司 2023-03-10 CN disclosed
CN-114907408-A Heterocyclic compound, intermediate thereof, preparation method and application thereof 武汉朗来科技发展有限公司 2022-08-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624041-B2 Heterocyclic compound and use thereof TRPC1, TRPC5, TRPC3 DDR1 1849/4885KIT 2021/4885TRPC5 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.