Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21713928 | 0.84 | CCR1 (0.33) | CCR1BACE1TACR1 | |
| SCHEMBL947122 | 0.75 | BACE1 (0.36) | CCR1BACE1 | |
| SCHEMBL20238785 | 0.74 | BACE1 (0.35) | BACE1 | |
| SCHEMBL24439805 | 0.71 | BACE1 (0.41) | BACE1 | |
| SCHEMBL17508765 | 0.71 | USP14 (0.34) | BACE1 | |
| SCHEMBL30128155 | 0.71 | ALDH1A1 (0.41) | BACE1TACR1 | |
| SCHEMBL4339126 | 0.71 | ALDH1A1 (0.41) | BACE1TACR1 | |
| SCHEMBL21493144 | 0.71 | BACE1 (0.41) | BACE1 | |
| SCHEMBL30976550 | 0.71 | BACE1 (0.41) | BACE1 | |
| SCHEMBL1001366 | 0.71 | MEN1 (0.36) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867553-A | Diaminopyrazolo [1,5-a ] pyrimidine-6-carbonitrile compounds as adenosine 2A receptor and adenosine 2B receptor antagonists | 巴格沃克斯研究有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-4121431-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | Bugworks Research, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2022149167-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2022-07-14 | — | — | WO | disclosed |