Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24176784 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4DHFRGPR183SLC6A3 | |
| Hydrochloric Acid SCHEMBL25363172 | 0.99 | SLC6A2 (0.36) | SLC6A2SLC6A4DHFRGPR183SLC6A3 | |
| SCHEMBL26019807 | 0.81 | EPHX2 (0.38) | SLC6A2SLC6A4DHFRSLC6A3EPHX2 | |
| Hydrochloric Acid SCHEMBL25361681 | 0.80 | EPHX2 (0.38) | SLC6A2SLC6A4DHFRSLC6A3EPHX2 | |
| SCHEMBL30603338 | 0.78 | SLC6A2 (0.38) | SLC6A2SLC6A4DHFRSLC6A3IDO1 | |
| SCHEMBL26019795 | 0.78 | SLC6A2 (0.38) | SLC6A2SLC6A4DHFRSLC6A3IDO1 | |
| SCHEMBL25363518 | 0.77 | P2RX7 (0.47) | DHFRGPR183EPHX2P2RX7 | |
| Hydrochloric Acid SCHEMBL28682527 | 0.77 | IDO1 (0.38) | SLC6A2SLC6A4DHFRSLC6A3IDO1 | |
| SCHEMBL29791929 | 0.76 | DHFR (0.40) | SLC6A2SLC6A4DHFRGPR183SLC6A3 | |
| Hydrochloric Acid SCHEMBL30289722 | 0.75 | DHFR (0.40) | SLC6A2SLC6A4DHFRGPR183SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907408-B | Heterocyclic compound, intermediate thereof, preparation method and application thereof | 武汉朗来科技发展有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114907408-A | Heterocyclic compound, intermediate thereof, preparation method and application thereof | 武汉朗来科技发展有限公司 | 2022-08-16 | — | — | CN | disclosed |