Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 5/20 | 0.68 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.68 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.66 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.65 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 3/20 | 0.62 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.61 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.61 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25098203 | 1.00 | P2RX3 (0.68) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL29353873 | 0.92 | P2RX3 (0.79) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL624619 | 0.92 | P2RX3 (0.79) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL14929510 | 0.92 | P2RX3 (0.79) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL14178286 | 0.92 | P2RX3 (0.79) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL14946389 | 0.92 | P2RX3 (0.79) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL3502130 | 0.92 | P2RX3 (0.79) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL31396265 | 0.91 | P2RX3 (0.77) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL20580517 | 0.89 | P2RX3 (0.67) | P2RX3P2RX2P2RX4GPR17P2RX1 | |
| SCHEMBL30848951 | 0.89 | P2RX3 (0.67) | P2RX3P2RX2P2RX4GPR17P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4277636-A1 | MODIFIED OLIGONUCLEOTIDES | Alnylam Pharmaceuticals, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022155418-A9 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| WO-2022155418-A1 | MODIFIED OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2022-07-21 | — | — | WO | disclosed |