Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.68 |
| ▸ | BRD4 | O60885 | 18/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24625520 | 1.00 | EGFR (0.68) | EGFRBRD4 | |
| SCHEMBL30620422 | 0.86 | EGFR (0.68) | EGFRBRD4 | |
| SCHEMBL270435 | 0.85 | BRD4 (0.76) | EGFRBRD4 | |
| Hydrochloric Acid SCHEMBL266755 | 0.84 | BRD4 (0.74) | EGFRBRD4 | |
| SCHEMBL271488 | 0.82 | BRD4 (0.80) | EGFRBRD4 | |
| SCHEMBL17915974 | 0.82 | BRD4 (0.78) | BRD4 | |
| SCHEMBL12111070 | 0.82 | BRD4 (0.73) | EGFRBRD4 | |
| SCHEMBL26394775 | 0.82 | BRD4 (0.68) | EGFRBRD4 | |
| SCHEMBL29793866 | 0.82 | BRD4 (0.68) | EGFRBRD4 | |
| SCHEMBL31163056 | 0.82 | BRD4 (0.76) | EGFRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778282-B | Pyrimidine micromolecule compound and application thereof | 温州医科大学 | 2022-07-22 | — | — | CN | disclosed |