Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.44 |
| ▸ | ACE | P12821 | 7/20 | 0.42 |
| ▸ | REN | P00797 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29765215 | 0.85 | ACE (0.52) | CAPN1ACERENKDM4EF2 | |
| SCHEMBL29765157 | 0.85 | ACE (0.52) | CAPN1ACERENKDM4EF2 | |
| SCHEMBL29666768 | 0.84 | ACE (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL29802004 | 0.83 | ACE (0.52) | ACERENOPRK1 | |
| SCHEMBL29802246 | 0.83 | ACE (0.52) | ACERENOPRK1 | |
| SCHEMBL30628782 | 0.83 | ACE (0.49) | ACERENOPRK1 | |
| SCHEMBL29802029 | 0.82 | ACE (0.48) | ACEREN | |
| SCHEMBL3871588 | 0.82 | CAPN1 (0.53) | CAPN1ACERENCTSBOPRK1 | |
| SCHEMBL29765195 | 0.82 | ACE (0.48) | CAPN1ACERENCTSB | |
| SCHEMBL23854819 | 0.81 | ACE (0.47) | CAPN1ACERENKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247338-A2 | COMPOSITIONS OF A BETA-HAIRPIN PEPTIDOMIMETIC AND AEROSOL DOSAGE FORMS THEREOF | Spexis AG (CH) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022106063-A2 | COMPOSITIONS OF A BETA-HAIRPIN PEPTIDOMIMETIC AND AEROSOL DOSAGE FORMS THEREOF | POLYPHOR AG (CH) | 2022-05-27 | — | — | WO | disclosed |