Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 8/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | CTSE | P14091 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | XPNPEP2 | O43895 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212823 | 0.89 | CAPN1 (0.61) | CAPN1CTSB | |
| SCHEMBL29794045 | 0.82 | CAPN1 (0.44) | CAPN1CTSBOPRK1RENACE | |
| SCHEMBL5521229 | 0.79 | CAPN1 (0.51) | CAPN1CTSBOPRK1RENMEN1 | |
| SCHEMBL5521222 | 0.79 | CAPN1 (0.51) | CAPN1CTSBOPRK1RENMEN1 | |
| SCHEMBL5273015 | 0.78 | OPRK1 (0.51) | OPRK1NTSR2NTSR1ACE | |
| SCHEMBL5273011 | 0.78 | OPRK1 (0.51) | OPRK1NTSR2NTSR1ACE | |
| SCHEMBL30522298 | 0.77 | CAPN1 (0.51) | CAPN1CTSBRENMEN1KMT2A | |
| SCHEMBL30060350 | 0.77 | CAPN1 (0.49) | CAPN1CTSBOPRK1RENMEN1 | |
| SCHEMBL30498898 | 0.77 | CAPN1 (0.49) | CAPN1CTSBRENMEN1KMT2A | |
| SCHEMBL30661451 | 0.76 | MEN1 (0.47) | OPRK1RENMEN1KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040758-A2 | BIORESPONSIVE POLYMERS | Interface Biologics Inc. (CA) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008053362-A2 | BIORESPONSIVE POLYMERS | INTERFACE BIOLOGICS, INC. (CA) | 2008-05-08 | — | — | WO | disclosed |