Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.63 |
| ▸ | HPGDS | O60760 | 2/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29794454 | 0.87 | CRBN (0.64) | CRBNHPGDSDDB1 | |
| SCHEMBL29794496 | 0.87 | CRBN (0.64) | CRBNHPGDSDDB1AR | |
| SCHEMBL29794446 | 0.87 | CRBN (0.64) | CRBNHPGDSDDB1AR | |
| SCHEMBL31348171 | 0.86 | CRBN (0.66) | CRBNHPGDSDDB1AR | |
| SCHEMBL29794441 | 0.86 | CRBN (0.61) | CRBNHPGDSDDB1ARMMP1 | |
| SCHEMBL29794472 | 0.86 | CRBN (0.63) | CRBNHPGDSDDB1MMP1MMP9 | |
| SCHEMBL23860197 | 0.85 | CRBN (0.70) | CRBNHPGDSDDB1EGFR | |
| SCHEMBL29794463 | 0.85 | CRBN (0.62) | CRBNHPGDSDDB1MMP1MMP9 | |
| SCHEMBL26814133 | 0.84 | CRBN (0.71) | CRBNDDB1EGFR | |
| SCHEMBL24414489 | 0.84 | CRBN (0.74) | CRBNHPGDSDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043817-A | SOS1 proteolysis regulator and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-09-13 | — | — | CN | disclosed |