Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.64 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.47 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29794446 | 0.93 | CRBN (0.64) | CRBNDDB1HPGDSARIKZF2 | |
| SCHEMBL29794454 | 0.89 | CRBN (0.64) | CRBNDDB1HPGDSALDH1A1CHRM2 | |
| SCHEMBL31348171 | 0.89 | CRBN (0.66) | CRBNDDB1HPGDSARIKZF2 | |
| SCHEMBL29794444 | 0.87 | CRBN (0.63) | CRBNDDB1HPGDSAR | |
| SCHEMBL29794471 | 0.87 | CRBN (0.63) | CRBNDDB1HPGDSAR | |
| SCHEMBL24670003 | 0.85 | CRBN (0.71) | CRBNDDB1HPGDSARIKZF2 | |
| SCHEMBL30043230 | 0.85 | CRBN (0.71) | CRBNDDB1HPGDSARIKZF2 | |
| SCHEMBL30312919 | 0.85 | CRBN (0.71) | CRBNDDB1HPGDSARIKZF2 | |
| Hydrochloric Acid SCHEMBL29207810 | 0.84 | CRBN (0.70) | CRBNDDB1HPGDSARALDH1A1 | |
| SCHEMBL24820799 | 0.84 | CRBN (0.72) | CRBNDDB1HPGDSARIKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043817-A | SOS1 proteolysis regulator and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-09-13 | — | — | CN | disclosed |