Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 19/20 | 1.00 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | LYN | P07948 | 1/20 | 0.61 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.61 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294087 | 0.93 | SYK (1.00) | SYKJAK2EGFRLCKLYN | |
| SCHEMBL3837515 | 0.83 | SYK (1.00) | SYKJAK2EGFRLCKLYN | |
| SCHEMBL1198317 | 0.82 | SYK (0.77) | SYKJAK2EGFRLCKLYN | |
| SCHEMBL30010055 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL2105664 | 0.79 | SYK (0.73) | SYKJAK2EGFRLCKLYN | |
| SCHEMBL30009798 | 0.78 | SYK (1.00) | SYK | |
| SCHEMBL2103190 | 0.78 | SYK (0.72) | SYKJAK2EGFRLCKLYN | |
| SCHEMBL14607333 | 0.78 | SYK (0.70) | SYKJAK2EGFRLCKLYN | |
| SCHEMBL17277999 | 0.78 | SYK (0.71) | SYKJAK2EGFRLCKLYN | |
| SCHEMBL12100695 | 0.77 | SYK (0.74) | SYKJAK2EGFRLCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945378-B | Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof | 休斯敦大学体系 | 2024-11-19 | — | — | CN | disclosed |
| CN-114945378-A | Feeder-layer and feeder-layer-free stem cell culture systems for stratified epithelial stem cells and uses related thereto | 休斯敦大学体系 | 2022-08-26 | — | — | CN | disclosed |
| EP-4041259-A1 | FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO | University of Houston System (US) | 2022-08-17 | — | — | EP | disclosed |