SCHEMBL30009798

SCHEMBL30009798

CNC(=O)COC1=C(C)CCC(Nc2ncc(F)c(Nc3ccc(OC)c(Cl)c3)n2)=C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SYK P43405 13/20 1.00
BCL6 P41182 7/20 0.55
NCOR2 Q9Y618 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30010055 0.85 SYK (1.00) SYK
SCHEMBL30010438 0.83 SYK (1.00) SYK
SCHEMBL3839578 0.81 SYK (1.00) SYK
SCHEMBL29794592 0.78 SYK (1.00) SYK
SCHEMBL31294087 0.78 SYK (1.00) SYK
SCHEMBL655635 0.77 BCL6 (0.80) SYKBCL6NCOR2
SCHEMBL14607343 0.76 SYK (0.68) SYKBCL6NCOR2
SCHEMBL2102179 0.76 BCL6 (0.72) SYKBCL6NCOR2
SCHEMBL2102021 0.75 BCL6 (0.71) SYKBCL6NCOR2
SCHEMBL2103957 0.75 BCL6 (0.71) SYKBCL6NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945378-B Feeder-based and feeder-free stem cell culture systems for stratified epithelial stem cells and related uses thereof 休斯敦大学体系 2024-11-19 CN disclosed
EP-4041259-A1 FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO University of Houston System (US) 2022-08-17 EP disclosed